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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1, kinase dead or dominant negative) under a CMV promoter. |
| Description: | Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (kinase dead or dominant negative), pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (kinase dead or dominant negative) |
| NCBI Acc. #: | NM_003161 |
| Gene ID: | 6198 |
| GI Number: | 4506736 |
| Fusion Tag: | C-terminus 6xHN tag |
| Promoter: | CMV |
| Titer: | 1E+10~1E+11 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Backgound: | RPS6KB1 gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. |
| Documents: | Please contact us to request the manual |
