Adenovirus RUNX3 (200 μl)

Adenovirus RUNX3 (200 μl)

Cat. #: M1157
Availability: In Stock
$719.00
-+

Product Category:

Human Adenovirus Type5 (dE1/E3) expressing Runt-related transcription factor 3  (RUNX3) under CMV promoter.


Description:

Runt-related transcription factor 3 (RUNX3), pre-made adenovirus, ready to ship and ready to use format.


Gene Name:

Runt-related transcription factor 3


ACCN:

BC013362


Gene ID:

864


GI Number:

33878242


Fusion Tag:

V5 tag at C-terminal


Promoter:

CMV


Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol


Background:

RUNX3 gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.


Documents:

Manual


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