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Description: | This recombinant human adenovirus type 5 (dE1/E3) expresses spermidine/spermine N1-acetyltransferase 1 (SAT1) under CMV promoter. |
Gene: | Spermidine/spermine N1-acetyltransferase 1 |
NCBI Acc. #: | M55580.1 |
Gene ID: | 6303 |
GI Number: | M55580 |
Fusion Tag: | No |
Promoter: | CMV |
Titer: | 1x1010~1x1011 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | Spermidine/spermine-N1-acetyltransferase (SSAT1) is a short-lived polyamine catabolic enzyme which catalyzes the acetylation of polyamines. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Induction of SSAT1 plays an important role in polyamine homoeostasis, since the N1-acetylated polyamines can be excreted or oxidized by acetylpolyamine oxidase. |
Documents: | Please contact us to request the manual |