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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Synuclein, Alpha (non A4 Component Of Amyloid Precursor) (SNCA) under a CMV promoter. |
| Description: | Synuclein, Alpha (non A4 Component Of Amyloid Precursor), pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Synuclein, Alpha (non A4 Component Of Amyloid Precursor) |
| NCBI Acc. #: | BC013293 |
| Gene ID: | 6622 |
| GI Number: | 15342041 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. |
| Storage: | -80°C |
| Documents: | Please contact us to request the manual |