Adenovirus SNCA (200 μl)

Product Category:

Human Adenovirus Type5 (dE1/E3) expressing  Synuclein, Alpha (non A4 Component Of Amyloid Precursor) (SNCA) under a CMV promoter.

Description:

Synuclein, Alpha (non A4 Component Of Amyloid Precursor), pre-packaged adenovirus, ready to ship and ready to use format.

Gene Name:

Synuclein, Alpha (non A4 Component Of Amyloid Precursor)

ACCN:

BC013293

Gene ID:

6622

GI Number:

15342041

Fusion Tag:

No

Promoter:

CMV

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

Storage:

-80°C

Documents:

Manual