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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Titin-cap (telethonin) under CMV promoter. |
| Description: | Titin-cap (telethonin), premade adenovirus, ready to ship and ready to use format. |
| Gene: | Titin-cap (telethonin) |
| NCBI Acc. #: | BC012628 |
| Gene ID: | 8557 |
| GI Number: | 15215002 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1E+10~1E+11 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. |
| Documents: | Please contact us to request the manual |
