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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Transforming Growth Factor, Beta Receptor I (activin A Receptor Type II-like Kinase, 53kDa) (TGFBR1).
Description:
ransforming Growth Factor, Beta Receptor I (activin A Receptor Type II-like Kinase, 53kDa), pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Transforming Growth Factor, Beta Receptor I (activin A Receptor Type II-like Kinase, 53kDa)
ACCN:
NM_004612
Gene ID:
7046
GI Number:
7046
Fusion Tag:
C-terminus V5 epitope or 6xHN tag
Promoter:
CMV
Titer:
1x1011~1x1012 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The protein encoded by TGFBR1 gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
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