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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Transforming Growth Factor, Beta Receptor I (activin A Receptor Type II-like Kinase, 53kDa) (TGFBR1). |
Description: | ransforming Growth Factor, Beta Receptor I (activin A Receptor Type II-like Kinase, 53kDa), pre-made adenovirus, ready to ship and ready to use format. |
Gene: | Transforming Growth Factor, Beta Receptor I (activin A Receptor Type II-like Kinase, 53kDa) |
NCBI Acc. #: | NM_004612 |
Gene ID: | 7046 |
GI Number: | 7046 |
Fusion Tag: | C-terminus V5 epitope or 6xHN tag |
Promoter: | CMV |
Titer: | 1x1011~1x1012 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | The protein encoded by TGFBR1 gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |
Documents: | Please contact us to request the manual |