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Human Adenovirus Type5 (dE1/E3) expressing regulator of G-protein signalling 2 (RGS2, also known as G0S8) under UBC promoter with co-expression of reporter mCherry under a separate CMV promoter. |
Gene Name: | Regulator of G-protein signalling 2 |
Symbol: | RGS2 |
Synonyms: | G0S8 |
NCBI Acc. #: | BC007049 |
Gene ID: | 5997 |
GI Number: | 13937881 |
Fusion Tag: | No |
Promoter: | UBC |
Titer: | 1E+11 ~ 1E+12 PFU/ml |
Storage Buffer: | DMEM with 2% BSA & 2.5% Glycerol |
Background: | Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. |
Documents: | Manual |