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Anti-Aldolase C Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Aldolase C rabbit polyclonal antibody |
Gene Name: | Fructose-bisphosphate aldolase C |
Synonyms: | Aldoc, ALDOC, ALDC, Aldolase C, Aldolase, Fructose-bisphosphate C |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Aldolase C |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 40 kDa |
Observed MW. | 40 kDa |
Uniprot ID: | P09972, P05063, P09117 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, hippocampus, cerebellum |
Background
ALDOC is one of the three aldolase isozymes (A, B, and C), encoded by three different genes. Aldolase C (fructose bisphosphate aldolase) is a key enzyme in the fourth step of glycolysis, as well as in the reverse pathway gluconeogenesis. It catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate (G3P), or glyceraldehyde, and dihydroxyacetone phosphate (DHAP) by aldol cleavage. As a result, it is a crucial player in ATP biosynthesis. In addition, ALDOC participates in the stress-response pathway for lung epithelial cell function during hypoxia and in the resistance of cerebellar Purkinje cells against excitotoxic insult.
Images
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Western blot analysis of ALDC (GB11825) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
