Your shopping cart is empty!
Anti-Alpha-synuclein Rabbit pAb (100 μl)
| Reactivity: | H,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Alpha-synuclein rabbit polyclonal antibody |
Gene Name: | Alpha-synuclein |
Synonyms: | SNCA, NACP, PARK1, PARK4, PD1, synuclein alpha, α-synuclein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse α-synuclein |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 14 kDa |
Observed MW. | 19 kDa |
Uniprot ID: | P37840, O55042, P37377 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 600 | brain, cerebral cortex |
IHC/IF | Mouse, Rat | 1:1000-1:2000 | brain, cerebellum |
Background
Alpha-synuclein is a protein that, in humans, is encoded by the SNCA gene. It is abundant in the brain while smaller amounts are found in the heart, muscles, and other tissues. In the brain, alpha-synuclein is found mainly at the tips of nerve cells (neurons) in specialized structures called presynaptic terminals. Within these structures, alpha-synuclein interacts with phospholipids and proteins. Presynaptic terminals release chemical messengers, called neurotransmitters, from compartments known as synaptic vesicles. The release of neurotransmitters relays signals between neurons and is critical for normal brain function.
Images
|
Western blot analysis of SNCA (GB11404) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using α-synuclein GB11404 at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin-embedded rat brain using α-synuclein GB11404 at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using α-synuclein GB11404 at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin-embedded rat cerebellum using α-synuclein GB11404 at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |