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Anti-Androgen receptor Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Androgen receptor rabbit polyclonal antibody |
Gene Name: | Androgen receptor |
Synonyms: | Dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, Androgen receptor, AIS, AR, DHTR |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | P10275, P19091, P15207 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 100-1: 1000 | heart, prostate, prostatic cancer, seminal vesicle, testis |
Background
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones.
Images
| Immunohistochemistry of paraffin embedded human prostate using AP (GB11253) at dilution of 1:500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse seminal vesicle using AP (GB11253) at dilution of 1:500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse seminal vesicle using AP (GB11253) at dilution of 1:500 (400x lens) |
| Immunofluorescence of paraffin embedded human prostatic cancer using AP (GB11253) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse heart using AP (GB11253) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using AP (GB11253) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat prostate using AP (GB11253) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
