AF488 Anti-Mouse CD40 Antibody (25 μg)

AF488 Anti-Mouse CD40 Antibody (25 μg)

Cat. #: FD1850
Availability: In Stock
$249.00
-+
Reactivity: Mouse    
Applications: FCM    
Host Species: Rat    
Isotype: Rat IgG2a, κ    
Clonality: Monoclonal    
Conjugation: AF488    
Synonyms: Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5
Background: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Gene ID: 21939
SwissProt: P27512
Concentration: 0.5 mg/mL    
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Documents: Please contact us to request the manual

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