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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | APC |
Synonyms: | T-cell antigen CD7,CD7,GP40,T-cell leukemia antigen,T-cell surface antigen Leu-9,TP41,TP41 |
Background: | CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion. |
Gene ID: | 924 |
SwissProt: | P09564 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
Documents: | Please contact us to request the manual |