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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | PE/TR |
Synonyms: | CD81 antigen,CD81,26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1.Tetraspanin-28,Tspan-28,APA1, TSPAN28 |
Background: | CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells. |
Gene ID: | 975 |
SwissProt: | P60033 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
Documents: | Please contact us to request the manual |