PerCP/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody (25 μg)

PerCP/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody (25 μg)

Cat. #: FD1246
Availability: In Stock
$219.00
-+
Reactivity: Mouse    
Applications: FCM    
Host Species: Rat    
Isotype: Rat IgM, κ    
Clonality: Monoclonal    
Conjugation: PerCP/Cyanine5.5    
Synonyms: B220
Background: CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Gene ID: 19264,5788
Concentration: 0.2 mg/mL    
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Documents: Please contact us to request the manual

LifeSct © 2024

Publications

text_heading

Our Location

405 East Gude Dr., Suite 205, Rockville, MD 20850, USA

1-240-715-2985