Purified Anti-Human CD279/PD-1 Antibody (25 μg)

Purified Anti-Human CD279/PD-1 Antibody (25 μg)

Cat. #: FD0526
Availability: In Stock
$169.00
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Reactivity: Human    
Applications: FCM    
Host Species: Mouse    
Isotype: Mouse IgG1, κ    
Clonality: Monoclonal    
Conjugation: Unconjugated    
Synonyms: PDCD1,PD1,Protein PD-1,hPD-1
Background: Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Gene ID: 3683
SwissProt: Q15116
Concentration: 0.5 mg/mL    
Buffer: PBS with 0.05% Proclin300
Storage: Store at 2~8°C. Do not freeze.
Documents: Please contact us to request the manual

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