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KO-Validated ARL6IP1 Rabbit pAb (20 μl)
| Reactivity: | Human |
| Applications: | WB, IHC, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | ARL6 interacting reticulophagy regulator 1 |
| Gene Symbol: | ARL6IP1 |
| Synonyms: | AIP1; ARMER; SPG61; ARL6IP; P1 |
| Gene ID: | 23204 |
| UniProt ID: | Q15041 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL6IP1 (NP_055976.1). |
| Dilution: | WB 1:500-1:2000; IF/IC 1:50-1:100 |
| Purification Method: | Affinity purification |
| Concentration: | 2.41 mg/mL |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ARL6IP1 polyclonal antibody |
Background
The gene ARL6IP1 belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene.
Images
_KO-WB_01.jpg?t=1709191337) | Western blot analysis of lysates from wild type (WT) and ARL6IP1 knockout (KO) 293T cells, using [KO Validated] ARL6IP1 Rabbit pAb (A19995) at 1:5000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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