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KO-Validated TTLL12 Rabbit pAb (20 μl)
| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | tubulin tyrosine ligase like 12 |
| Gene Symbol: | TTLL12 |
| Synonyms: | dJ526I14.2; 12 |
| Gene ID: | 23170 |
| UniProt ID: | Q14166 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 485-644 of human TTLL12 (NP_055955.1). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.49 mg/mL |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TTLL12 polyclonal antibody |
Background
Enables H4K20me3 modified histone binding activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytoplasm.
Images
_KO-WB_01.jpg?t=1709191333) | Western blot analysis of lysates from wild type (WT) and TTLL12 knockout (KO) 293T cells, using [KO Validated] TTLL12 Rabbit pAb (A19994) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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