Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Neurofilament Medium rabbit polyclonal antibody |
Gene Name: | Neurofilament medium polypeptide |
Synonyms: | Nefm, NEFM, NEF3, NF-M, NFM, Neurofilament, Medium polypeptide, Neurofilament medium |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Neurofilament Medium |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoskeleton |
Predicted MW. | 96 kDa |
Observed MW. | 150 kDa |
Uniprot ID: | P08553, P12839 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 1500 | brain, cerebrum cortex cerebellum, spinal cord |
Background
Neurofilament medium polypeptide (NF-M) is encoded by the NEFM gene. Neurofilaments are type IV intermediate filament heteropolymers composed of light (NEFL), medium (this protein), and heavy (NEFH) chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage.
Images
Western blot analysis of Neurofilament Medium (GB11763) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |