Anti-5HT2C Receptor Rabbit pAb (100 μl)

Anti-5HT2C Receptor Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB111002-100
Availability: In Stock
$259.00
-+
Reactivity: M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

5HT2C Receptor rabbit polyclonal antibody

Gene Name:

5-hydroxytryptamine receptor 2C

Synonyms:

5-ht-1c receptor, 5HT1C, 5HT2C, 5HTR2C, G protein-coupled, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2C, Htr1c, HTR2C, serotonin 1c receptor, serotonin 2c receptor, Serotonin 5-HT-2C receptor

Immunogen:

KLH conjugated Synthetic peptide corresponding to Mouse 5HT2C Receptor

Isotype:

IgG

Purity:

Affinity purification

Predicted MW.

52 kDa

Observed MW.

52 kDa

Uniprot ID:

P34968, P08909




Product Usage Information

Applications

Species

Dilution

Positive tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, cerebral cortex , cerebellum, hippocampus




Background

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.5HT2C is a 45 kDa 7TM receptor for serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5HT2C ligation regulates mood, appetite, and motivation. 5HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety and migrane headaches. Multiple isoforms of 5HT2C can be generated by RNA editing. Human 5HT2C shares 89% aa sequence identity with mouse and rat 5HT2C.




Images

Western blot analysis of 5-HT2C (GB111002) at dilution of 1: 500




Storage

Storage Store at -20°C for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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