Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | 5-hydroxytryptamine receptor 3B |
Synonyms: | 5-HT3-B, Serotonin receptor 3B, Htr3b, 5 hydroxytryptamine serotonin receptor 3B, Htr3b, Serotonin gated ion channel subunit |
Immunogen: | Recombinant protein corresponding to Mouse 5HT3B receptor |
Uniprot ID: | Q9JHJ5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 50 kDa / 50-55 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | kidney |
Background
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine , a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude.
Images
Western blot analysis of Prkar2b (GB111373) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |