Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein) |
Gene ID: | 4747 |
Immunogen: | Synthesized peptide derived from human Neurofilament |
Uniprot ID: | P07196 |
Source: | Mouse/IgG2b, Kappa |
Concentration: | 1 mg/ml |
Purity: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
IHC/IF | Human | 1: 200-1: 500 | brain |
Background
neurofilament, light polypeptide(NEFL) Homo sapiens Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008],
Images
Immunohistochemistry analysis of paraffin embedded human brain using 68kDa Neurofilament/NF-L (GB14120) at dilution of 1: 200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |