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Anti-68kDa Neurofilament/NF-L Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | 68kDa Neurofilament/NF-L rabbit polyclonal antibody |
Gene Name: | Neurofilament light polypeptide |
Synonyms: | NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein, Nefl, Nf68, Nfl |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse 68kDa Neurofilament |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 62 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | P08551, P19527 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebellum |
Background
Neurofilament light polypeptide also called NF-L; Neurofilament triplet L protein; 68 kDa neurofilament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. NF-L is the most abundant of the three neurofilament proteins and, as the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. Belongs to the intermediate filament family.
Images
 | Western blot analysis of Nefl (GB112968) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
