Anti-ABCA7 Rabbit pAb (100 μl)

Anti-ABCA7 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB113271-100
Availability: In Stock
$259.00
-+
Reactivity: M    
Applications: IHC/IF    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

ABCA7 rabbit polyclonal

Gene Name:

ATP-binding cassette sub-family A member 7

Synonyms:

ABCA SSN, ABCA7, ABCX, Autoantigen SS N, Macrophage ABC transporter

Immunogen:

KLH conjugated Synthetic peptide

corresponding to Mouse ABCA7

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Cell membrane, Cytoplasm

Uniprot ID:

Q91V24




Product Usage Information

IHC/IF

Mouse

1: 1500-1: 3000

brain




Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.




Images

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

ABCA7 (GB113271) at dilution of 1: 3000




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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