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Anti-ACSL3 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ACSL3 rabbit polyclonal |
Gene Name: | Long-chain-fatty-acid--CoA ligase 3 |
Synonyms: | Long-chain acyl-CoA synthetase 3, Arachidonate--CoA ligase, ACS3, ACSL3, FACL3, LACS 3, LACS3, PRO2194 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ACSL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 80 kDa |
Observed MW. | 80 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 600 | HepG2, MCF-7, THP-1, 293T, Jurkat, A-431 |
Background
ACSL3, also named as ACS3, FACL3 and LACS3, belongs to the ATP-dependent AMP-binding enzyme family. Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). The antibody is specific to ACSL3.
Images
 | Western blot analysis of ACSL3 (GB113698) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
