Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ADAM10 rabbit polyclonal antibody |
Gene Name: | Disintegrin and metalloproteinase |
Synonyms: | AD10, AD18, CD156c, HsT18717, MADM, RAK, kuz, CDw15 |
Immunogen: | Recombinant protein corresponding to Mouse ADAM10 (Human 91%, Rat 97%) |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 84 kDa |
Observed MW. | 60-70 (mature)/90-100 (precursor ) kDa |
Uniprot ID: | O14672 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | Jurkat, HepG2, MCF-7 |
Background
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.
Images
Western blot analysis of ADAM10 (GB111343) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |