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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AHSG rabbit polyclonal antibody |
Gene Name: | Alpha-2-HS-glycoprotein |
Synonyms: | Countertrypin, Fetuin-A, Ahsg, Fetua, 59 kDa bone sialic acid-containing protein, A2HS, Ahsg alpha-2-HS-glycoprotein, Ba alpha 2 glycoprotein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AHSG |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P29699, P24090 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 4000 | liver, liver cancer, lung cancer |
Background
Fetuin-A, also named as Alpha2-HS glycoprotein (AHSG), is a member of cystatin superfamily of protease inhibitors. It is a highly expressed glycoprotein in various fetal tissues whereas it is mainly expressed by the liver in adults. Fetuin A, an extracellular inhibitor of transforming growth factor β, is a profibrogenic stimulus in liver disease. Circulating fetuin-A may be a beneficial serum biomarker in the detection of liver and vascular fibrosis progression in patients with non-alcoholic fatty liver disease.
Images
| Immunohistochemistry of paraffin embedded mouse liver using AHSG (GB112376) at dilution of 1:700 (400x lens) |
| Immunohistochemistry of paraffin embedded rat liver using AHSG (GB112376) at dilution of 1:700 (400x lens) |
| Immunofluorescence of paraffin embedded human liver cancer using AHSG (GB112376) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded human lung cancer using AHSG (GB112376) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse liver using AHSG (GB112376) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded rat liver using AHSG (GB112376) at dilution of 1:650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
