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Anti-ALDH4A1 Rabbit pAb (100 μl)
| Reactivity: | H & H,M,R & H,M,R & M |
| Applications: | WB & IHC/IF & ICC/IF & IEM |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ALDH4A1 rabbit polyclonal antibody |
Gene Name: | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial |
Synonyms: | P5C dehydrogenase, Aldehyde dehydrogenase family 4 member A1, Aldh4a1, L-glutamate gamma-semialdehyde dehydrogenase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ALDH4A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Predicted MW. | 62 kDa |
Observed MW. | 62 kDa |
Uniprot ID: | P30038, Q8CHT0, P0C2X9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 600 | heart, lung, brain |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 2400 | colon cancer, kidney, liver, lung, pancreas, placenta, small intestine, testis |
Background
ALDH4A1(Aldehyde dehydrogenase family 4 member A1) is also named as ALDH4, P5CDH,P5C dehydrogenase and belongs to the aldehyde dehydrogenase family. P5CDH is a mitochondrial matrix NAD(+)-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate.Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2).
Images
| Western blot analysis of Aldh4a1 (GB112430) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded mouse kidney using Aldh4a1 (GB112430) at dilution of 1: 1200 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse small intestine using Aldh4a1 (GB112430) at dilution of 1: 1200 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse testis using Aldh4a1 (GB112430) at dilution of 1: 1200 (400x lens) |
 | Immunofluorescence of paraffin embedded human colon cancer using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded human liver using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded human pancreas using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse kidney using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse liver using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse lung using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse pancreas using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded rat kidney using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
| Immunofluorescence of paraffin embedded rat liver using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
| Immunofluorescence of paraffin embedded rat pancreas using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
| Immunofluorescence of paraffin embedded rat placenta using Aldh4a1 (GB112430) at dilution of 1: 400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
