Reactivity: | R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | DNA oxidative demethylase ALKBH2 |
Synonyms: | |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ALKBH2 |
Uniprot ID: | Q6P6J4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 27 kDa / 29 kDa |
Product Usage Information
WB | Rat | 1: 2000-1: 3000 | liver, lung |
Background
Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
Images
Western blot analysis of ALKBH2 (GB115121) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |