Reactivity: | R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | AMPK alpha 2 rabbit polyclonal |
Gene Name: | 5'-AMP-activated protein kinase catalytic subunit alpha-2 |
Synonyms: | AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, AMPKA2, AMPKα2, PRKAA, PRKAA2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AMPK alpha 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 1000-1: 2000 | kidney, skeletal muscle |
Background
PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belongs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity. The protein can be ubiquitinated.
Images
Immunohistochemistry analysis of paraffin-embedded rat kidney using AMPK2 (GB113685) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using AMPK2 (GB113685) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |