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Anti-APLP2 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | APLP2 rabbit polyclonal |
Gene Name: | Amyloid-like protein 2 |
Synonyms: | Amyloid like protein 2, Amyloid protein homolog, APLP-2, APLP2, APPH, APPL2, CDEBP, CDEI box binding protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse APLP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 80 kDa |
Observed MW. | 80 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 600 | HeLa, HepG2 |
Background
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Images
 | Western blot analysis of APLP2 (GB113384) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
