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Anti-ARHGAP11A Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ARHGAP11A rabbit polyclonal antibody |
Gene Name: | Rho GTPase-activating protein 11A |
Synonyms: | Rho-type GTPase-activating protein 11A, Arhgap11a, Kiaa0013 |
Immunogen: | Recombinant protein corresponding to Mouse ARHGAP11A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 108 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q6P4F7, Q80Y19 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 1000-1: 2000 | kidney |
Background
This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line.
Images
 | Western blot analysis of ARHGAP11A (GB112745) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
