Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Activating signal cointegrator 1 complex subunit 1 |
Synonyms: | ASC 1 complex subunit p50, ASC1p50, ASCC1, CGI 18, RP11 150D20.4, Trip4 complex subunit p50 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ASCC1 |
Uniprot ID: | Q9D8Z1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 41 kDa / 48 kDa |
Product Usage Information
WB | Human | 1: 1000-1: 2000 | 293T, A549, K562 |
Background
Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction.
Images
Western blot analysis of ASCC1 (GB114866) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |