Your shopping cart is empty!
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ATF7 rabbit polyclonal antibody |
Gene Name: | Cyclic AMP-dependent transcription factor ATF-7 |
Synonyms: | cAMP-dependent transcription factor ATF-7, Activating transcription factor 7, Transcription factor ATF-A, Atf7, Atf7 protein, MGC57182, MGC31554, C130020M04Rik |
Immunogen: | Recombinant protein corresponding to Mouse ATF7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8R0S1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 800-1: 1600 | heart |
Background
ATF7 plays important functions in early cell signaling. Binds the cAMP response element (CRE) , a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.
Images
|
Immunohistochemistry of paraffin embedded mouse heart using ATF7 (GB111579) at dilution of 1:800 (300x lens) |
|
Immunohistochemistry of paraffin embedded rat heart using ATF7 (GB111579) at dilution of 1:800 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
