Reactivity: | H,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ATG16L1 rabbit polyclonal antibody |
Gene Name: | Autophagy-related protein 16-1 |
Synonyms: | ATG16L1, autophagy related 16-like 1 (S. cerevisiae), APG16L, ATG16A, ATG16L, IBD10, WDR30, Autophagy related 16 like 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human ATG16L1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Rat | 1: 500-1: 4000 | corpus striatum, kidney, lymph node |
Background
Autophagy related 16 like 1 is a protein that in humans is encoded by the ATG16L1 gene. Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.
Images
Immunohistochemistry of paraffin embedded human kidney using Atg16L1 (GB11876) at dilution of 1:2000 (300x lens) |
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Immunohistochemistry of paraffin embedded rat lymph node using Atg16L1 (GB11876) at dilution of 1:2000 (350x lens) |
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Immunofluorescence of paraffin embedded rat corpus striatum using Atg16L1 (GB11876) at dilution of 1:500 (200x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |