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Anti-ATP6J/ATP6V1G1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | V-type proton ATPase subunit G 1 |
Synonyms: | ATP6G, ATP6G1, ATP6GL, ATP6J, ATP6V1G1, V ATPase 13 kDa subunit 1, V ATPase subunit G 1, Vma10 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ATP6J/ATP6V1G1 |
Uniprot ID: | Q9CR51 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 14 kDa / 14 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | kidney |
Background
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.
Images
| Western blot analysis of ATP6V1G1 (GB114957) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
