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Anti-ATP6V1B2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | V-type proton ATPase subunit B, brain isoform |
Synonyms: | ATP6B1B2, ATP6B2, HO57, V ATPase subunit B 2, VATB, Vma2, VPP3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ATP6V1B2 |
Uniprot ID: | P62814 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 57 kDa / 58 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 3000 | heart, brain |
Background
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load.
Images
| Western blot analysis of ATP6V1B2 (GB115014) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
