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Anti-Angiotensinogen Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Angiotensinogen rabbit polyclonal antibody |
Gene Name: | Angiotensinogen |
Synonyms: | AGT, ANHU, SERPINA8, angiotensinogen, hFLT1, Ang I, Ang II, Ang III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensin-3 , ANRT, AT-2, PAT , SERPINA8, Alpha 1 antiproteinase antitrypsin |
Immunogen: | Recombinant protein corresponding to Mouse Angiotensinogen |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 52 kDa |
Observed MW. | 52 kDa |
Uniprot ID: | P11859 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | liver, kidney |
Background
Angiotensinogen is also known as renin substrate. Human angiotensinogen is 452 amino acids long, but other species have angiotensinogen of varying sizes. The first 12 amino acids are the most important for activity Angiotensinogen is an α-2-globulin produced constitutively and released into the circulation mainly by the liver. It is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Plasma angiotensinogen levels are increased by plasma corticosteroid, estrogen, thyroid hormone, and angiotensin II levels.
Images
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Western blot analysis of AGT (GB11535) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
