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Recombinant Anti-Annexin-6/ANXA6 Mouse mAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Annexin A6 |
Synonyms: | 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II, CPB-II, Chromobindin-20, Lipocortin VI, Protein III, p68, p70, Anxa6, Anx6, Annexin-6 |
Immunogen: | Recombinant protein corresponding to Mouse Annexin-6 |
Uniprot ID: | P14824 |
Isotype: | IgG1 |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Melanosome |
Predicted MW. / Observed MW. | 76 kDa / 72 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | PC-2, liver, lung |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | endometrial Cancer, Small intestine |
Background
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. It is characterised by a conserved core domain which binds to phospholipids in a Ca2+ dependent manner and a unique amino terminal region which may confer binding specificity. The Annexin family has been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
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Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
