Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Anterior Gradient 2 rabbit polyclonal antibody |
Gene Name: | Anterior gradient protein 2 homolog |
Synonyms: | AG-2, mAG-2, Protein Gob-4, Secreted cement gland protein XAG-2 homolog, Agr2, Gob4 |
Immunogen: | Recombinant protein corresponding to Mouse Anterior Gradient 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted, Cytoplasm |
Uniprot ID: | O95994, O88312, D3ZIA7 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 4000 | breast cancer, colon, lung, small intestine, stomach |
Background
AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
Images
Immunohistochemistry of paraffin embedded human breast cancer using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded human colon using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse small intestine using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse stomach using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat small intestine using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded human breast cancer using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse lung using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse small intestine using AGR2 (GB111327) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded rat stomach using AGR2 (GB111327) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |