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Anti-Axin 2 Rabbit pAb (100 μl)
| Reactivity: | R & R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Axin 2 rabbit polyclonal |
Gene Name: | Axin-2 |
Synonyms: | AXIN2, AXIL, ODCRCS, axin 2, Axin like protein, Axin2, Axis inhibition protein 2, Axin-2 |
Immunogen: | Recombinant protein corresponding to Mouse Axin 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 500-1: 3000 | spleen |
IF | Rat | 1: 500-1: 1000 | spleen |
Background
Axin-2 also known as axin-like protein (Axil) or axis inhibition protein 2 (AXIN2) or conductin presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin
Images
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Immunohistochemistry analysis of paraffin-embedded rat spleen using Axin 2 (GB11607) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
