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| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | BAAT1 rabbit polyclonal |
| Gene Name: | BRCA1-associated ATM activator 1 |
Synonyms: | Brat1, BRAT1, BAAT1, C7orf27, RMFSL, BRCA1 associated ATM activator 1, NEDCAS |
| Immunogen: | Recombinant protein corresponding to Mouse BAAT1 |
| Isotype: | IgG |
| Purity: | Affinity purification |
| Subcellular location: | Nucleus, Cytoplasm |
| Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1:500-1:3500 | cerebral infarction, lung |
IF | Mouse, Rat | 1:250-1:500 | cerebral infarction, lung |
Background
BRCA1-associated ATM activator 1 encoded by ubiquitously expressed BRAT1 gene, interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and the ATM (ataxia telangiectasia mutated) protein. The protein is required for activation of ATM following ionizing radiation and may act by regulating dephosphorylation of ATM. The protein is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse cerebral infarction using BAAT1 (GB11772) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat cerebral infarction using BAAT1 (GB11772) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using BAAT1 (GB11772) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
