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Anti-BEND3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | BEND3 rabbit polyclonal antibody |
Gene Name: | BEN domain-containing protein 3 |
Synonyms: | Bend3, Kiaa1553 |
Immunogen: | Recombinant protein corresponding to Mouse BEND3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 94 kDa |
Observed MW. | 100 kDa |
Uniprot ID: | Q5T5X7, Q6PAL0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain |
Background
The BEND3 is a transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination. Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites.
Images
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Western blot analysis of BEND3 (GB111532) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
