Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | BMP4 rabbit polyclonal |
Gene Name: | Bone morphogenetic protein 4 |
Synonyms: | BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, bone morphogenetic protein 4, ZYME, zbmp-4, DVR4 |
Immunogen: | Recombinant protein corresponding to Mouse Mouse BMP4. |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1000-1: 4000 | bone |
IF | Mouse, Rat | 1: 1000-1: 2000 | bone |
Background
BMP4 is a polypeptide belonging to the TGF-βsuperfamily of proteins, which binds to 2 different types of serine-threonine kinase receptors known as BMPR1 and BMPR2. Signal transduction via these receptors occurs via Smad and map kinase pathways to effect transcription of its target genes. Like other bone morphogenetic proteins, it is involved in bone and cartilage development, specifically tooth and limb development and fracture repair, playing an important role in the onset of endochondral bone formation in humans. It has been shown to be involved in muscle development, bone mineralization, and ureteric bud development.
Images
 |
Immunohistochemistry analysis of paraffin-embedded mouse bone using BMP4 (GB11520) at dilution of 1:2000. |
 |
Immunohistochemistry analysis of paraffin-embedded mouse bone using BMP4 (GB11520) at dilution of 1:2000. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
