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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | BMP4 rabbit polyclonal antibody |
Gene Name: | Bone morphogenetic protein 4 |
Synonyms: | BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, bone morphogenetic protein 4, ZYME, zbmp-4, DVR4 |
Immunogen: | Recombinant protein corresponding to Mouse BMP4. |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 47 kDa |
Observed MW. | 47 kDa |
Uniprot ID: | P21275, Q06826 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, muscle, liver |
Background
BMP4 is a polypeptide belonging to the TGF-βsuperfamily of proteins, which binds to 2 different types of serine-threonine kinase receptors known as BMPR1 and BMPR2. Signal transduction via these receptors occurs via Smad and map kinase pathways to effect transcription of its target genes. Like other bone morphogenetic proteins, it is involved in bone and cartilage development, specifically tooth and limb development and fracture repair, playing an important role in the onset of endochondral bone formation in humans. It has been shown to be involved in muscle development, bone mineralization, and ureteric bud development.
Images
 | Western blot analysis of BMP4 (GB11521) at dilution of 1: 500 |
|
Western blot analysis of BMP4 (GB11521) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
