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Anti-BMPR1A Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Bone morphogenetic protein receptor type-1A |
Synonyms: | Ia10q23del, Activin receptor like kinase 3, ACVRLK3, ALK 3, ALK3, BMP type 1A receptor, BMPR-1A, CD292, SKR5h1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse BMPR1A |
Uniprot ID: | P36895 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 60 kDa / 58 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 800 | liver, testis |
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Images
| Western blot analysis of BMPR1A (GB115448) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
