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Anti-Band 3/AE 1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Band 3/AE 1 rabbit polyclonal |
Gene Name: | Band 3 anion transport protein |
Synonyms: | AE-1, AE1, Anion exchange protein 1, Anion exchanger 1, band 3, CD233, SLC4A1, MEB3, Solute carrier family 4 member 1 |
Immunogen: | Recombinant protein corresponding to Mouse Band 3/AE 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 3000-1: 6000 | kidney, spleen, striatum |
Background
Anion exchanger 1 (AE1), also known as band 3, is a 95-100 kDa transmembrane glycoprotein which is abundantly expressed in erythrocyte plasma membrane and mediates the electroneutral exchange of Cl- and HCO3-. It contains a 52-55 kDa C-terminal membrane crossing domain and a 43 kDa N-terminal cytoplasmic domain. Degradation of band 3 protein occurred during erythrocyte aging. The oxidative stress can also activate the proteolysis of band 3 through caspases.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using AE1 (GB113603) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using AE1 (GB113603) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded mouse spleen using AE1 (GB113603) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat spleen using AE1 (GB113603) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded mouse striatum using AE1 (GB113603) at dilution of 1: 6000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
