Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Bok rabbit polyclonal antibody |
Gene Name: | Bcl-2-related ovarian killer protein |
Synonyms: | Apoptosis activator Mtd, Protein matador, Bok, Mtd, BCL2L9, BOKL |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Bok |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q792S6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 1500 | kidney, liver |
Background
The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as Anti-or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.
Images
Immunofluorescence of paraffin embedded human liver using B0K (GB112952) at dilution of 1:750 (400x lens) | |
Immunofluorescence of paraffin embedded mouse kidney using B0K (GB112952) at dilution of 1:750 (400x lens) | |
Immunofluorescence of paraffin embedded rat kidney using B0K (GB112952) at dilution of 1:750 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |