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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Bora rabbit polyclonal antibody |
Gene Name: | Protein aurora borealis |
Synonyms: | Aurora borealis, bora, BORA, C13orf34, Chromosome 13 open reading frame 34, FLJ22624, HsBora, Protein aurora borealis, RP11-342J4.2 |
Immunogen: | Recombinant protein corresponding to Mouse Bora |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 100-1: 400 | epencephalon, heart, lung, testis |
Background
Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation, bipolar spindle assembly and chromosome segregation during mitosis. Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1. Bora is localized to the nucleus until mitosis is initiated, when it then translocates to the cytoplasm. This translocation is dependent on activated Cdc2, which releases Bora to bind and activate ARK-1 in the cytoplasm.
Images
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Immunohistochemistry of paraffin embedded mouse lung using Bora (GB11647) at dilution of 1:200 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using Bora (GB11647) at dilution of 1:200 (400x lens) |
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Immunofluorescence of paraffin embedded mouse epencephalon using Bora (GB11647) at dilution of 1:200 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using Bora (GB11647) at dilution of 1:200 (400x lens) |
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Immunofluorescence of paraffin embedded rat testis using Bora (GB11647) at dilution of 1:200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
