Reactivity: | R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Carbonic Anhydrase 5A/CA5A rabbit polyclonal |
Gene Name: | Carbonic anhydrase 5A, mitochondrial |
Synonyms: | Carbonate dehydratase VA, CA Y, Carbonic anhydrase VA, CA-VA, Ca5, Car5, Car5a, Ca5a |
Immunogen: | Recombinant protein corresponding to Mouse Carbonic Anhydrase 5A/CA5A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 1500-1: 3000 | heart |
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis.
Images
Immunohistochemistry analysis of paraffin-embedded rat heart using CA5A (GB112713) at dilution of 1: 3000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |