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Anti-Carbonic Anhydrase 9/CA9 Mouse mAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Carbonic anhydrase 9 |
Synonyms: | Carbonate dehydratase IX, CA-IX, MN, G250, Carbonic anhydrase IX, Membrane antigen MN, P54/58N, RCC-associated antigen G250, CA9, pMW1 |
Immunogen: | Recombinant protein corresponding to Human CA9 |
Uniprot ID: | Q16790 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. / Observed MW. | 58/200 kDa / 49/54 kDa |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1500 | stomach, renal carcinoma, colon cancer |
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known.
Images
| Immunohistochemistry analysis of paraffin embedded human stomach using CA-9 (GB121184) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human renal carcinoma using CA-9 (GB121184) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human colon cancer using CA-9 (GB121184) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
